GP-write will include whole genome engineering of human cell lines and other organisms of agricultural and public health significance. Thus, the Human Genome Project-write (HGP-write) will be a critical core activity within GP-write focused on synthesizing human genomes in whole or in part. It will also be explicitly limited to work in cells, and organoids derived from them only. Because of the special challenges surrounding human genomes, this activity will include an expanded examination of the ethical, legal and social implications of the project.
The potential benefits of HGP-write to India include providing new solutions to diseases like malaria, dengue and chikungunya. The tools, techniques and technologies that are going to be developed through HGP-write will be universally applicable to all organisms, especially at an earlier stage for organisms with smaller genomes (for example, viruses), towards building individual genes and genomes efficiently and in an inexpensive manner.